Overview:
This meta-analysis evaluated the efficacy of nasal saline irrigation (NSI) in managing allergic rhinitis (AR) across children and adults. The analysis included randomized controlled trials comparing NSI to no treatment or to other standard interventions, assessing symptom reduction, medication use, and safety. Subgroup analyses evaluated differences between age groups and solution types (hypertonic vs. isotonic).
The Takeaways:
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NSI significantly improved AR symptoms in both adults and children when compared to no treatment. Benefits included relief from congestion, rhinorrhea, sneezing, and itching.
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When combined with medications, NSI offered additional benefit in adults, although not statistically superior to medication alone in children.
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Compared to medication alone, saline irrigation was less effective in adults, but comparable in children.
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Hypertonic saline was more effective than isotonic saline for children.
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NSI was safe overall, with only minor adverse events such as nasal irritation. One child withdrew from a study due to a reaction, but no adults experienced significant adverse events.
Why It Matters:
This study reinforces the role of saline irrigation as a well-tolerated, non-pharmacologic therapy that can improve allergic rhinitis symptoms and potentially reduce reliance on medications. It highlights NSI’s versatility across age groups and its role as a safe alternative for children and pregnant women, especially when considering hypertonic solutions.
The Link to Allermi:
Allermi incorporates saline irrigation into its multi-modal treatment plans for allergic rhinitis. This meta-analysis supports that strategy—demonstrating that NSI enhances symptom relief, supports mucociliary clearance, and provides a medication-sparing effect. Allermi’s use of saline reflects evidence-based care tailored to both adult and pediatric needs.
For more details, refer to the full study: Role of nasal saline irrigation in the treatment of allergic rhinitis in children and adults: A systematic review
